Custom peptide synthesis

Peptides are compounds formed by connecting amino acids as basic units through peptide bonds. They have multiple biological activities such as antibacterial, antiviral, antioxidant, and immunomodulatory, and are widely used in disease research, drug and vaccine development, and other fields. We provide a wide range of active peptides for scientific research, covering multiple popular product categories such as label peptides, drug peptides, cell-penetrating peptides, amino acids and their deriva

Apr 15th,2025 310 Views

I. Core technology advantages

1. Internationally leading synthesis technology

Kangna Bio's peptide synthesis platform integrates fully automatic peptide synthesis, advanced microwave technology and peptide chain extension technology, and can flexibly select liquid phase peptide synthesis (LPPS) or solid phase peptide synthesis (SPPS) according to the sequence. The synthesis platform combined with the fully automatic synthesizer can not only guarantee a monthly synthesis throughput of up to 12,000, but also ensure batch stability between peptide products, with a single synthesis success rate of up to 98%.

Support synthesis range: wide length range (2-200aa), complex modified peptides (phosphorylation/glycosylation/fluorescence labeling, etc.)

2. Full-dimensional quality control system

Detection Dimension	Technical means	Quality Control Standards
Purity analysis	HPLC/UPLC	≥95% conventional quality control
Molecular weight verification	MALDI-TOF/MS	Error＜0.1%
Biological Activity	Cell assay/ELISA	Batch-to-batch variation <5%
stability	Accelerated experiment/long-term sample retention	Comply with ICH guidelines

3. Multi-field application product matrix

Application Areas	Representative Products
Targeted therapy	iRGD tumor-penetrating peptide, GLP-1 analog (liraglutide), angiotensin derivatives
Anti-infective agents	Polymyxin B sulfate, human defensin HNP-1, daptomycin custom modifications
Diagnostic reagent development	FITC labeled peptides, isotope (125I) labeled peptides, biotin-avidin system modified peptides
Innovative raw materials for medical beauty	Palmitoyl hexapeptide-12 (promoting collagen), copper tripeptide GHK-Cu (repair), acetyl tetrapeptide-2 (anti-wrinkle)

II. Customized service process

1. Demand confirmation stage

Submission method: Official website work order/technical consultant connection

Key elements:

*Customer Name:		*Email Address:
*Company/Organization Name:		*Contact Number:
*Peptide Name:		*Quantity Required:
*Packed into:	(bottle)	*purity:
CAS No.:		Peptide salt form:
Peptide sequence
N-terminal modification type:		C-terminal modification type:
Other modifications:		Disulfide bonds:
Solubility Test:	DMSO/DMF ( ) H2O ( ) Other solvents ( )
Leave us a message:

2. Process development stage

Molecular simulation: conformational analysis using MOE software

Synthesis route: segmented strategy optimization (modular synthesis is used for peptides >30aa)

Risk assessment: prediction of difficult sites (such as multiple consecutive hydrophobic amino acids)

3. Production quality control stage

Cycle management: conventional peptides (5-15 working days), complex modified peptides (15-30 working days)

Process monitoring: staged HPLC detection (crude product → purification → freeze-drying)

Delivery standard: complete analysis report (including MS, HPLC spectrum, COA document)

III. Technical service system

Professional support: Synthesis team led by a PhD
Equipment support: ABI Symphony® fully automatic synthesizer, Waters UPLC and other cutting-edge equipment
Storage and transportation: -20℃ cold chain transportation

Gene-edited mice

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