Our animal modeling team leverages standardized protocols and advanced analytics for real-time physiological monitoring, ensuring validated models with enhanced reproducibility.
Known Bio has integrated multiple authoritative and comprehensive compound databases, and combined with independent research and development technologies, it has built a massive and structurally diverse library of its own compounds, providing a solid data foundation for virtual screening.
Gene-edited mice are animal models in which the mouse genome is precisely modified through modern biotechnology (such as CRISPR-Cas9, TALENs, or ES cell targeting).
PK studies of suckling mice (usually referring to young mice ≤ 21 days after birth) are crucial for pediatric drug development, as their physiological characteristics (immature organ development and low metabolic enzyme activity) significantly affect the drug ADME process.
Peptides are compounds formed by connecting amino acids as basic units through peptide bonds. They have multiple biological activities such as antibacterial, antiviral, antioxidant, and immunomodulatory, and are widely used in disease research, drug and vaccine development, and other fields. We provide a wide range of active peptides for scientific research, covering multiple popular product categories such as label peptides, drug peptides, cell-penetrating peptides, amino acids and their deriva
Shanghai Known Biotechnology Co., Ltd. is located in the Shanghai Hongqiao Biomedicine Headquarters Park. It is a new technology company focusing on the field of biotechnology and is committed to providing the global biopharmaceutical industry with full-chain innovative solutions from molecular discovery to preclinical research. The company's strategic layout is based on three major R&D centers: The Beijing laboratory focuses on custom peptide synthesis and stability optimization; As a preclinical research center, the Wuhan laboratory focuses on the construction of gene-edited animal models, disease efficacy evaluation, and pharmacology and toxicology verification to create a precision medicine research platform; Guangzhou Laboratory uses AI-driven high-throughput screening and innovative drug development as an engine to accelerate the transformation of the first-in-class innovative drug pipeline. The three laboratories work together in depth to form a closed-loop innovation ecosystem of "molecular design-animal verification-drug development", and continue to deliver breakthrough therapies in the fields of tumors, metabolism and neurological diseases.
