Octreotide acetate

Basic Description

Structure and function ​:
Octreotide is a synthetic cyclic octapeptide, a long-acting analog of natural somatostatin, which works by binding to somatostatin receptors (SSTR2/5):
1. ​​Inhibit hormone secretion​ ​：Reduces levels of growth hormone (GH), insulin, glucagon and gastrin.
2. ​​Anti-tumor effects​ ​：Inhibit hormone release and cell proliferation of neuroendocrine tumors (such as carcinoid and glucagonoma).
3. ​​Vasoactivity​ ​：Reduce visceral blood flow and treat esophageal varicose bleeding.

​ ​Application Areas​ ​:
• ​Clinical treatment ​: Acromegaly, neuroendocrine tumors, refractory diarrhea.
• ​​Research ​：Somatostatin receptor signaling mechanism and development of tumor targeted therapy.

Molecular formula

C₄₉H₆₆N₁₀O₁₀S₂·C₂H₄O₂

Molecular weight

1079.30 (including acetate)

purity

>99%

form

Lyophilized powder

Storage conditions

Store at -20°C away from light and moisture