Ceruletide

Basic Description

Structure and function ​:
Ceruletide is a genus of Hyla caerulea ) A decapeptide isolated from the skin, which has a similar structure to cholecystokinin (CCK) and can activate cholecystokinin receptors (CCK-A/B receptors). Its main functions include:
1. ​​Stimulate gallbladder contraction​ ​：Promote bile excretion and is used for gallbladder function assessment.
2. ​​Promote pancreatic enzyme secretion​ ​：Activate pancreatic acinar cells for the study of pancreatic exocrine function.
3. ​​Anti-inflammatory and analgesic​ ​：Inhibit the production of inflammatory mediators by regulating the release of neuropeptides.

​ ​Research Applications​ ​:
• Gallbladder dynamics study (diagnostic gallbladder contraction test)
• Analysis of pancreatic secretion mechanism
• Gastrointestinal disease models (e.g. acute pancreatitis)

Core Structure

Pyr-Gln-Asp-Tyr-Thr-Gly-Trp-Met-Asp-Phe-NH₂

Molecular formula

C₅₈H₇₃N₁₃O₂₁S

Molecular weight

1352.3

purity

>95%

form

Lyophilized powder

Storage conditions

Store at -20°C away from light