Deslorelin

Basic Description

Structure and function:
Deslorelin is a synthetic decapeptide that is a gonadotropin-releasing hormone (GnRH) agonist.
Its main effect is to stimulate the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by activating the GnRH receptor.
An initial transient increase in LH and FSH secretion is followed by a decrease in LH and FSH levels due to receptor downregulation, which results in suppression of ovarian or testicular function.
In vitro and in vivo studies:
In vitro, deslorelin can significantly activate GnRH receptors.
In in vivo experiments, deslorelin can effectively inhibit ovarian or testicular function and reduce sex hormone levels.
In clinical applications, deslorelin is used in assisted reproductive technology, treatment of prostate cancer and certain gynecological diseases.

​ ​Three-letter sequence​

​ ​Single letter sequence​

CAS Number

Molecular formula

Molecular weight

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light