Exendin-4

Basic Description

​ Structure and function:
Exenatide is a natural peptide extracted from lizard saliva and consists of 39 amino acids.
It is a glucagon-like peptide-1 (GLP-1) receptor agonist that promotes insulin secretion and inhibits glucagon secretion by mimicking the effects of GLP-1, thereby lowering blood sugar levels.
Exenatide can also slow gastric emptying, reduce appetite, and help with weight management.
In vitro and in vivo studies:
In in vitro experiments, exenatide can significantly stimulate the secretion of insulin from pancreatic β cells.
In vivo studies, exenatide was able to effectively lower blood glucose levels and improve cardiovascular risk factors in patients with type 2 diabetes.
Exenatide has shown good glucose-lowering and cardiovascular protective effects in clinical trials.

​ ​Three-letter sequence​

​ ​Single letter sequence​

CAS Number

Molecular formula

Molecular weight

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light