Fertirelin

Basic Description

Structure and function:
Fetirelin is a synthetic decapeptide that is a gonadotropin-releasing hormone (GnRH) agonist.
Its main effect is to stimulate the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by activating the GnRH receptor.
An initial transient increase in LH and FSH secretion is followed by a decrease in LH and FSH levels due to receptor downregulation, which inhibits ovarian function.
In vitro and in vivo studies:
In in vitro experiments, fetirelin can significantly activate GnRH receptors.
In in vivo experiments, fetirelin can effectively inhibit ovarian function and reduce estrogen levels.
In clinical applications, fetirelin is used for ovarian stimulation in assisted reproductive technology and for the treatment of certain gynecological diseases.

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​ ​Single letter sequence​

CAS Number

Molecular formula

Molecular weight

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light