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  • Ganirelix
  • Ganirelix

Ganirelix

Ganirelix is ​​a synthetic decapeptide that belongs to the class of gonadotropin-releasing hormone (GnRH) antagonists. Its main action is to inhibit the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by blocking the GnRH receptor, thereby preventing premature ovulation. Ganirelix is ​​used for ovarian stimulation in assisted reproductive technology.

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Product Overview

Basic Description

Structure and function:
Ganirelix is ​​a synthetic decapeptide that is a gonadotropin-releasing hormone (GnRH) antagonist.
Its main effect is to inhibit the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by blocking the GnRH receptor, thereby preventing premature ovulation.
Ganirelix is ​​used for ovarian stimulation in assisted reproductive technology.
In vitro and in vivo studies:
In in vitro experiments, ganirelix can significantly inhibit the activity of GnRH receptors.
In vivo, ganirelix was able to effectively inhibit the secretion of LH and FSH and prevent premature ovulation.
In clinical applications, Ganirelix is ​​used to stimulate the ovaries and control ovulation timing in assisted reproductive technology.

​Three-letter sequence​

Ac-D-Nal(2)-D-4Cl-Phe-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2

​Single letter sequence​

Ac-DND-4F-D-3P-SYDCLRPDA-NH2

CAS Number

124904-93-4

Molecular formula

C60H84ClN17O11

Molecular weight

1185.94 g/mol

Product Attributes

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light


Instructions
  • After receiving the product, please store it in accordance with the conditions recommended in the instructions. Unless otherwise specified, the relevant products are all lyophilized powders. Since trace amounts of polypeptides are deposited in the tube during the lyophilization process, forming a very thin or invisible polypeptide layer,
    Before capping the tube, we recommend centrifuging at about 8,000-12,000 g for 10-30 seconds to allow the peptides attached to the tube cap or tube wall to accumulate at the bottom of the tube.
  • Please refer to relevant literature for the specific optimal working concentration, or explore and optimize through experiments based on the purpose of the experiment and specific cells and animals.
Our company can provide customized synthesis of high-polypeptide, virtual screening of compounds, Animal disease model construction,
Drug safety verification,
Application technology support for gene editing animals, etc.
For specific application consultation, please contact the sales department.

We look forward to your inquiries:

Sales Department 1: Manager Han
Mobile phone: 18701856899
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Email: 18701856899@163.com