Ganirelix

Name: Ganirelix
Brand: Shanghai Kangna Biotechnology Co., Ltd. official website
Availability: InStock
Rating: 5 (1 reviews)

Ganirelix is a synthetic gonadotropin-releasing hormone (GnRH) antagonist, primarily used in assisted reproductive technology (ART) for ovarian stimulation cycles.By competitively blocking pituitary GnRH receptors, it rapidly suppresses luteinizing hormone (LH) release, effectively preventing premature ovulation.Ganirelix is characterized by its rapid onset and short duration of action, allowing precise control of ovulation induction and improving oocyte retrieval efficiency. It is a key medication in in vitro fertilization (IVF) treatment.

Inquiry View Quote List

Product Details
Technical Support

Product Overview

Basic Description	Structure and Function: Ganirelix is a synthetic decapeptide belonging to the class of gonadotropin-releasing hormone (GnRH) antagonists. It competitively binds to GnRH receptors, inhibiting the action of endogenous GnRH and thereby reducing gonadotropin secretion. It is primarily used in assisted reproductive technology (ART) for ovarian stimulation, preventing premature LH surges and improving pregnancy rates. In Vitro and In Vivo Studies: In vitro studies demonstrate that Ganirelix effectively suppresses GnRH receptor activity. Animal studies show that Ganirelix significantly reduces serum LH and FSH levels. Clinical trials confirm its safety and efficacy in ART, supporting its use in IVF protocols.
Complete sequence	Pyr-His-Trp-Ser-Tyr-D-Phe-Leu-Arg-Pro-Gly-NH2
Simplify sequence	PHWSTYDPLRPG
CAS	123246-29-7
Molecular formula	C58H74N16O10
Molecular weight	1184.3 g/mol

Product Attributes

purity	>98%
form	Lyophilized powder
Storage conditions	Store at -20°C in a cool, dry place

Instructions

After receiving the product, please store it in accordance with the conditions recommended in the instructions. Unless otherwise specified, the relevant products are all lyophilized powders. Since trace amounts of polypeptides are deposited in the tube during the lyophilization process, forming a very thin or invisible polypeptide layer,
Before capping the tube, we recommend centrifuging at about 8,000-12,000 g for 10-30 seconds to allow the peptides attached to the tube cap or tube wall to accumulate at the bottom of the tube.

Please refer to relevant literature for the specific optimal working concentration, or explore and optimize through experiments based on the purpose of the experiment and specific cells and animals.

Our company can provide customized synthesis of high-polypeptide, virtual screening of compounds, Animal disease model construction,
Drug safety verification, Application technology support for gene editing animals, etc.
For specific application consultation, please contact the sales department.

We look forward to your inquiries:

Sales Department 1: Manager Han
Mobile phone: 18701856899

WeChat: 18701856899

QQ: 1295139147

Email: 18701856899@163.com

Ganirelix

Product Details

Technical Support