GLP-1 (7-37) Glucagon-like peptide

Basic Description

​ Structure and function:
· GLP-1 (7-37) is a polypeptide consisting of 31 amino acids.
It is the active fragment of glucagon-like peptide-1 (GLP-1) and is secreted primarily by L cells in the intestine.
By activating the GLP-1 receptor, GLP-1 (7-37) can promote insulin secretion from pancreatic β cells and inhibit the release of glucagon, thereby lowering blood glucose levels.
GLP-1 (7-37) also slows gastric emptying and reduces appetite, which can help control body weight.
In vitro and in vivo studies:
In vitro, GLP-1 (7-37) can significantly increase insulin secretion and inhibit glucagon secretion.
In vivo experiments, GLP-1 (7-37) can effectively reduce postprandial blood glucose levels and improve glycated hemoglobin (HbA1c) levels in patients with type 2 diabetes.
Clinical trials have shown that GLP-1 (7-37) can reduce the risk of cardiovascular events while lowering blood sugar.

​ ​Three-letter sequence​

​ ​Single letter sequence​

CAS Number

Molecular formula

Molecular weight

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light