Gonadorelin

Basic Description

Structure and function:
Gonadorelin is a synthetic decapeptide that is an analog of gonadotropin-releasing hormone (GnRH).
Its main effect is to stimulate the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by activating the GnRH receptor.
An initial transient increase in LH and FSH secretion is followed by a decrease in LH and FSH levels due to receptor downregulation, which results in suppression of ovarian or testicular function.
In vitro and in vivo studies:
In in vitro experiments, gonadorelin can significantly activate GnRH receptors.
In vivo, gonadorelin can effectively stimulate the secretion of LH and FSH, and inhibit the secretion of sex hormones when used for a long time.
In clinical applications, gonadorelin is used for ovarian stimulation in assisted reproductive technology and for the treatment of certain gynecological diseases.

​ ​Three-letter sequence​

​ ​Single letter sequence​

CAS Number

Molecular formula

Molecular weight

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light