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  • Retatrutide
  • Retatrutide

Retatrutide

Retatrutide is an innovative triple receptor agonist that simultaneously targets GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide) and glucagon receptors. It is mainly used to treat type 2 diabetes and obesity, significantly improving blood sugar control and promoting weight loss through multiple mechanisms. Clinical studies have shown that Retatrutide performs well in blood sugar reduction, weight loss and metabolic regulation, providing a breakthrough option for the treatment of metabolic diseases.

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  • Technical Support

Product Overview

Basic Description

Structure and function:
Retaglutide is a synthetic peptide that is a triple agonist of the GLP-1, GIP, and glucagon receptors.
Its main effect is to lower blood sugar levels by activating these receptors to promote insulin secretion and inhibit glucagon secretion.
Retaglutide also has weight loss and cardiovascular protective effects.
In vitro and in vivo studies:
In in vitro experiments, retaglutide can significantly increase insulin secretion and inhibit glucagon secretion.
In vivo experiments, retaglutide was able to effectively lower blood glucose levels and reduce body weight in patients with type 2 diabetes.
In clinical applications, retaglutide is used to treat type 2 diabetes and obesity.

​Three-letter sequence​

H - Tyr - Aib - Glu - Gly - Thr - Phe - Thr - Ser - Asp - Tyr - Ser - Ile - Aib - Leu - Asp - Lys - Ile - Ala - Gln - {20diacid - gamma - Glu - (AEEA)2 - Lys}-Ala - Phe - Val - Gln - Trp - Leu - Ile - Ala - Gly - Gly - Pro - Ser - Ser - Gly - Ala - Pro - Pro - Pro - Ser - NH2

​Single letter sequence​

HYAE(20diacid - gamma - Glu - (AEEA)2 - K)AFVQWLIAGGPS SGA PPPS - NH2

CAS Number

2023788-19-2

Molecular formula

C221H342N46O68

Molecular weight

4731.33 g/mol

Product Attributes

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light


Instructions
  • Please store the product immediately according to the recommended conditions in the instructions upon receipt. Unless otherwise specified, all products are freeze-dried powders. Since trace amounts of peptides are deposited in the tube during the freeze-drying process, forming a very thin or invisible peptide layer, we recommend centrifuging at about 8,000-12,000g for 10-30 seconds in a centrifuge before opening the tube cap, so that the peptides attached to the tube cap or tube wall are aggregated at the bottom of the tube.
  • Please refer to relevant literature for the specific optimal working concentration, or explore and optimize through experiments based on the purpose of the experiment and specific cells and animals.
Our company can provide customized synthesis of high-polypeptide, virtual screening of compounds, Animal disease model construction,
Drug safety verification,
Application technology support for gene editing animals, etc.
For specific application consultation, please contact the sales department.

We look forward to your inquiries:

Sales Department 1: Manager Han
Mobile phone: 18701856899
WeChat: 18701856899
QQ: 1295139147
Email: 18701856899@163.com