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  • Taspoglutide
  • Taspoglutide

Taspoglutide

Tasiroglutide is a synthetic peptide drug that belongs to the glucagon-like peptide-1 (GLP-1) receptor agonist. It is composed of 39 amino acids and its half-life in the body is prolonged by chemical modification. By activating the GLP-1 receptor, tasiroglutide can promote insulin secretion in pancreatic β cells and inhibit the release of glucagon, thereby lowering blood sugar levels.

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Product Overview

Basic Description

Structure and function:
Tasirolitide is a synthetic peptide drug that is a glucagon-like peptide-1 (GLP-1) receptor agonist.
It is composed of 39 amino acids, which have been chemically modified to prolong its half-life in the body.
By activating the GLP-1 receptor, taseroglutide can promote insulin secretion from pancreatic β cells and inhibit the release of glucagon, thereby lowering blood glucose levels.
Tasirolid also slows gastric emptying and reduces appetite, which can help control body weight.
In vitro and in vivo studies:
In in vitro experiments, tasirolid significantly increased insulin secretion and inhibited glucagon secretion.
In vivo experiments, tasirolitin can effectively reduce postprandial blood glucose levels and improve glycated hemoglobin (HbA1c) levels in patients with type 2 diabetes.
Clinical trials have shown that tasirolitinib can reduce the risk of cardiovascular events while lowering blood sugar.

​Three-letter sequence​

​Single letter sequence​

HGDGSFSDEMNTILDNLAARDFINWLIQTKITD

CAS Number

197922-42-2

Molecular formula

C 164 H 252 N 44 O 55 S

Molecular weight

3752.13

Product Attributes

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light


Instructions
  • After receiving the product, please store it in accordance with the conditions recommended in the instructions. Unless otherwise specified, the relevant products are all lyophilized powders. Since trace amounts of polypeptides are deposited in the tube during the lyophilization process, forming a very thin or invisible polypeptide layer,
    Before capping the tube, we recommend centrifuging at about 8,000-12,000 g for 10-30 seconds to allow the peptides attached to the tube cap or tube wall to accumulate at the bottom of the tube.
  • Please refer to relevant literature for the specific optimal working concentration, or explore and optimize through experiments based on the purpose of the experiment and specific cells and animals.
Our company can provide customized synthesis of high-polypeptide, virtual screening of compounds, Animal disease model construction,
Drug safety verification,
Application technology support for gene editing animals, etc.
For specific application consultation, please contact the sales department.

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