Teriparatide

Basic Description

Structure and function ​:
Teriparatide is the N-terminal 1-34 active fragment of human parathyroid hormone (PTH), which regulates bone metabolism in both directions by activating the PTH/PTHrP receptor (PPR) of osteoblasts:
1. ​​Promote bone formation​ ​：Intermittent administration can stimulate osteoblast differentiation and increase bone density.
2. ​​Anti-bone resorption ​：Inhibit osteoclast activity and reduce bone loss.

​ ​Application Areas​ ​:
• ​Clinical treatment ​: FDA-approved osteoporosis medication (particularly for patients at high risk of fracture).
• ​​Research ​：Bone metabolism regulation mechanism, bone tissue engineering (such as development of bone regeneration materials).

Complete sequence

Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val

Simplify sequence

SVSEIQLMHNLGKHLNSMERVEWLRKKLQDV

Molecular formula

C₁₈₁H₂₉₁N₅₅O₅₁S₂

Molecular weight

4117.8

purity

>99%

form

Lyophilized powder

Storage conditions

Store at -80°C away from light