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  • Mazdutide
  • Mazdutide

Mazdutide

Mazdutide is an innovative GLP-1 (glucagon-like peptide-1) and GCG (glucagon) dual receptor agonist, mainly used to treat type 2 diabetes and obesity. It enhances insulin secretion, suppresses appetite and promotes energy consumption through dual mechanisms, thereby significantly improving blood sugar control and effectively reducing weight. Clinical studies have shown that Mazdutide performs well in both blood sugar reduction and weight loss, providing a new treatment option for patients with metabolic diseases.

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  • Technical Support

Product Overview

Basic Description

Structure and function:
Mastolide is a synthetic peptide that is a dual agonist of GLP-1 and GIP receptors.
Its main effect is to lower blood sugar levels by activating these receptors to promote insulin secretion and inhibit glucagon secretion.
Mastolide also has the effects of weight loss and cardiovascular protection.
In vitro and in vivo studies:
In in vitro experiments, Mashidu peptide can significantly increase the secretion of insulin and inhibit the secretion of glucagon.
In in vivo experiments, Mashidu peptide can effectively lower blood sugar levels and reduce body weight in patients with type 2 diabetes.
In clinical applications, Mashidu peptide is used to treat type 2 diabetes and obesity.

​Three-letter sequence​

His - {Aib}-Gln - Gly - Thr - Phe - Thr - Ser - Asp - Tyr - Ser - Lys - Tyr - Leu - Asp - Glu - Lys - Lys - Ala - Lys - {AEEA - AEEA - γGlu - nonadecanoic acid}-Glu - Phe - Val - Glu - Trp - Leu - Leu - Glu - Gly - Gly - Pro - Ser - Ser - Gly - NH2

​Single letter sequence​

H - {Aib}-QG TFT SDY SKYLDE KKAK - {AEEA - AEEA - γGlu - nonadecanoic acid}-EFVE WLL EGGPS SG - NH2

CAS Number

2259884-03-0

Molecular formula

C210H322N46O67

Molecular weight

4563.06g/mol

Product Attributes

purity

>98%

form

Lyophilized powder

Storage conditions

Store at -20°C/-80°C away from light


Instructions
  • Please store the product immediately according to the recommended conditions in the instructions upon receipt. Unless otherwise specified, all products are freeze-dried powders. Since trace amounts of peptides are deposited in the tube during the freeze-drying process, forming a very thin or invisible peptide layer, we recommend centrifuging at about 8,000-12,000g for 10-30 seconds in a centrifuge before opening the tube cap, so that the peptides attached to the tube cap or tube wall are aggregated at the bottom of the tube.
  • Please refer to relevant literature for the specific optimal working concentration, or explore and optimize through experiments based on the purpose of the experiment and specific cells and animals.
Our company can provide customized synthesis of high-polypeptide, virtual screening of compounds, Animal disease model construction,
Drug safety verification,
Application technology support for gene editing animals, etc.
For specific application consultation, please contact the sales department.

We look forward to your inquiries:

Sales Department 1: Manager Han
Mobile phone: 18701856899
WeChat: 18701856899
QQ: 1295139147
Email: 18701856899@163.com